Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244815 | 0.80 | EPHX1 (0.52) | NPC1RAB9AMAPTHTTEPHX1 | |
| Formanilide SCHEMBL7025878 | 0.76 | ALDH1A1 (0.59) | NPC1RAB9AMAPTHTTALDH1A1 | |
| SCHEMBL7648977 | 0.70 | GAA (0.47) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL8410032 | 0.69 | SLC22A12 (0.51) | ALDH1A1 | |
| SCHEMBL5519988 | 0.67 | ALDH1A1 (0.41) | NPC1RAB9AMAPTEPHX1EPHX2 | |
| SCHEMBL7028849 | 0.66 | — | — | |
| SCHEMBL7913709 | 0.65 | TSHR (0.45) | NPC1RAB9AMAPTEPHX1EPHX2 | |
| SCHEMBL6783917 | 0.65 | RAPGEF4 (0.46) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL6991764 | 0.65 | ALDH1A1 (0.47) | MAPTEPHX1EPHX2ALDH1A1CA2 | |
| SCHEMBL2094001 | 0.65 | NPC1 (0.41) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002041871-A9 | COMPOSITION COMPRISING AN IMEXON OR DERIVATIVES THEREOF AND LIPIDS | UNIV TEXAS (US) | 2003-05-30 | — | — | WO | disclosed |