SCHEMBL7025902

SCHEMBL7025902

C=CCCC(=O)C(=C)C1CCC(C)CC1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.34
FAAH O00519 3/20 0.32
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7023469 0.84 FAAH (0.33) KMT2AFAAH
SCHEMBL180345 0.82 CES2 (0.37) KMT2AFAAHNPC1
SCHEMBL7020777 0.82 CES2 (0.37) KMT2AFAAHNPC1
SCHEMBL7020253 0.82 CES2 (0.37) KMT2AFAAHNPC1
SCHEMBL7029420 0.81 AAK1 (0.30)
SCHEMBL7024876 0.73 EPHX1 (0.38) FAAH
SCHEMBL7021892 0.73 EPHX1 (0.42) FAAH
SCHEMBL370951 0.70 KMT2A (0.35) KMT2AFAAH
SCHEMBL526441 0.69
SCHEMBL1052197 0.69 SMN1; SMN2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1063229-B1 Alpha, beta-unsaturated ketones GIVAUDAN SA (CH) 2003-02-19 EP disclosed
US-6184419-B1 HAVING A GREEN-GALBANUM, FRESH (METALLIC, UNDECATRIENE TYPE) AND FRUITY-PINEAPPLE AND/OR FRUITY-CASSIS ODOR; AN INTENSE AND LONG LASTING ODOR; PERFUMES; HOUSEHOLD AND LAUNDRY PRODUCTS; COSMETICS GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 2001-02-06 US disclosed
EP-1063229-A1 Alpha, beta-unsaturated ketones Givaudan SA (CH) 2000-12-27 EP disclosed