SCHEMBL180345

SCHEMBL180345

C=CCCC(=O)C(=C)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
FAAH O00519 4/20 0.33
KMT2A Q03164 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
ALDH1A1 P00352 2/20 0.32
GAA P10253 1/20 0.32
EPHX1 P07099 1/20 0.32
TSHR P16473 1/20 0.31
MAPT P10636 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
ABCC4 O15439 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7020777 1.00 CES2 (0.37) CES2CES1FAAHKMT2AHDAC8
SCHEMBL7020253 1.00 CES2 (0.37) CES2CES1FAAHKMT2AHDAC8
SCHEMBL7023469 0.98 FAAH (0.33) CES2CES1FAAHKMT2AMAPT
SCHEMBL7025902 0.82 KMT2A (0.34) FAAHKMT2ANPC1
SCHEMBL7029420 0.80 AAK1 (0.30)
SCHEMBL7023776 0.79 CES2 (0.34) CES2CES1FAAHKMT2AHDAC8
SCHEMBL7020043 0.79 CES2 (0.34) CES2CES1FAAHKMT2AHDAC8
SCHEMBL7020053 0.79 CES2 (0.34) CES2CES1FAAHKMT2AHDAC8
SCHEMBL29634830 0.79 CES2 (0.41) CES2CES1FAAHKMT2AHDAC8
SCHEMBL7021892 0.76 EPHX1 (0.42) FAAHALDH1A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559703-B2 Fragrance composition GIVAUDAN SA (CH) 2026-02-24 US claimed
EP-4655373-A1 BIODEGRADABLE PERFUME COMPOSITION Givaudan SA (CH) 2025-12-03 EP claimed
WO-2025202258-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2025-10-02 WO claimed
US-12421475-B2 High performing, high impact bloom accord with a top, medium, and base note mixture INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-09-23 US claimed
US-12404479-B2 Laundry detergent composition containing graft copolymer and benefit agent THE PROCTER & GAMBLE COMPANY (US) 2025-09-02 US claimed
EP-4555060-A1 LAUNDRY DETERGENT COMPOSITION CONTAINING GRAFT COPOLYMER AND BENEFIT AGENT The Procter & Gamble Company (US) 2025-05-21 EP claimed
WO-2024213536-A1 FRAGRANCE COMPOSITION GIVAUDAN SA (CH) 2024-10-17 WO claimed
US-20240301331-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-09-12 US claimed
WO-2024156688-A1 BIODEGRADABLE PERFUME COMPOSITION GIVAUDAN SA (CH) 2024-08-02 WO claimed
EP-4407019-A1 BIODEGRADABLE PERFUME COMPOSITION Givaudan SA (CH) 2024-07-31 EP claimed
EP-2111443-A2 BENEFIT AGENT DELIVERY COMPOSITIONS The Procter and Gamble Company (US) 2009-10-28 EP claimed
WO-2009052643-A1 ANTI-MALODOUR COMPOSITIONS GIVAUDAN SA (CH) 2009-04-30 WO claimed
WO-2008100601-A2 BENEFIT AGENT DELIVERY COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2008-08-21 WO claimed
US-20080200363-A1 Perfumes, brighteners, insect repellants, flavors, vitamins, fabric softeners, skin care agents; increasing potency, reducing cost PROECTER & GAMBLE COMPANY, THE 2008-08-21 US claimed
EP-1848702-A2 PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS Flexitral, Inc. (US) 2007-10-31 EP claimed
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions FLEXITRAL, INC. 2006-09-14 US claimed
WO-2006085048-A2 PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS FLEXITRAL, INC. (US) 2006-08-17 WO claimed
EP-1063229-B1 Alpha, beta-unsaturated ketones GIVAUDAN SA (CH) 2003-02-19 EP claimed
US-6184419-B1 HAVING A GREEN-GALBANUM, FRESH (METALLIC, UNDECATRIENE TYPE) AND FRUITY-PINEAPPLE AND/OR FRUITY-CASSIS ODOR; AN INTENSE AND LONG LASTING ODOR; PERFUMES; HOUSEHOLD AND LAUNDRY PRODUCTS; COSMETICS GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 2001-02-06 US claimed
EP-1063229-A1 Alpha, beta-unsaturated ketones Givaudan SA (CH) 2000-12-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559703-B2 Fragrance composition DHCR24, OPRD1, OR10J3 CES2 1163/4885CES1 954/4885FAAH 55/4885
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions TAS2R10, TAS2R9, OR10J3 CES2 2699/4885CES1 3882/4885FAAH 345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.