Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.92 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.92 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.69 |
| ▸ | MPO | P05164 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | NQO2 | P16083 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571512 | 1.00 | MTNR1A (0.92) | MTNR1AMTNR1BTRPV1KMT2AMEN1 | |
| SCHEMBL1129551 | 1.00 | MTNR1A (0.92) | MTNR1AMTNR1BTRPV1KMT2AMEN1 | |
| SCHEMBL31036086 | 0.96 | MTNR1A (0.87) | MTNR1AMTNR1BTRPV1KMT2AMEN1 | |
| SCHEMBL3815621 | 0.95 | MTNR1A (0.83) | MTNR1AMTNR1BTRPV1KMT2AMEN1 | |
| SCHEMBL5616635 | 0.92 | MTNR1A (0.85) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL1129785 | 0.92 | MTNR1A (0.77) | MTNR1AMTNR1BTRPV1KMT2AMEN1 | |
| SCHEMBL14907361 | 0.91 | MTNR1A (0.75) | MTNR1AMTNR1BTRPV1KMT2AMEN1 | |
| SCHEMBL3815984 | 0.91 | MTNR1A (0.75) | MTNR1AMTNR1BTRPV1KMT2AMEN1 | |
| SCHEMBL14907359 | 0.90 | MTNR1A (0.74) | MTNR1AMTNR1BTRPV1HTR1A | |
| SCHEMBL155073 | 0.89 | TRPV1 (0.78) | MTNR1AMTNR1BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11772085-B2 | Far superior oxidation catalysts based on macrocyclic compounds | CARNEGIE MELLON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| US-20210086171-A1 | FAR SUPERIOR OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | CARNEGIE MELLON UNIVERSITY | 2021-03-25 | — | — | US | disclosed |
| US-10926248-B2 | Far superior oxidation catalysts based on macrocyclic compounds | CARNEGIE MELLON UNIVERSITY (US) | 2021-02-23 | — | — | US | disclosed |
| US-20180304247-A1 | FAR SUPERIOR OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | CARNEGIE MELLON UNIVERSITY | 2018-10-25 | — | — | US | disclosed |
| EP-0914206-B1 | LONG-LIVED HOMOGENOUS OXIDATION CATALYSTS | UNIV CARNEGIE MELLON (US) | 2002-12-11 | — | — | EP | disclosed |
| EP-1064284-B1 | HYPNOTIC BETA-CARBOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS | MACEF (FR) | 2002-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10926248-B2 | Far superior oxidation catalysts based on macrocyclic compounds | ME3, SOD1, DUOX1 | MTNR1A 2666/4885MTNR1B 3515/4885TRPV1 4286/4885 |
| US-20180304247-A1 | FAR SUPERIOR OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | ME3, SOD1, DUOX1 | MTNR1A 2666/4885MTNR1B 3515/4885TRPV1 4286/4885 |
| US-11772085-B2 | Far superior oxidation catalysts based on macrocyclic compounds | SOD1, ME3, ME2 | MTNR1A 2991/4885MTNR1B 3782/4885TRPV1 4215/4885 |
| US-20210086171-A1 | FAR SUPERIOR OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | ME3, ME2, ME1 | MTNR1A 3379/4885MTNR1B 3997/4885TRPV1 4054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.