Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236512 | 0.85 | RAB9A (0.50) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL2634610 | 0.84 | RIPK1 (0.64) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL180384 | 0.82 | NPC1 (0.73) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL7027390 | 0.81 | AOC3 (0.52) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL17266198 | 0.81 | MEN1 (0.67) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL4836068 | 0.81 | MEN1 (0.63) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL18316998 | 0.81 | KMT2A (0.54) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL3650924 | 0.81 | HSD11B1 (0.58) | KMT2AMEN1NPC1RAB9ACA12 | |
| Hydrochloric Acid SCHEMBL11786759 | 0.81 | NPC1 (0.70) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL7027999 | 0.80 | CA12 (0.51) | KMT2AMEN1NPC1RAB9ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |