Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14323435 | 0.76 | ALOX15 (0.48) | ALOX15ALDH1A1TSHRKMT2ATDP1 | |
| SCHEMBL14331466 | 0.76 | ALOX15 (0.48) | ALOX15ALDH1A1TSHRKMT2ATDP1 | |
| SCHEMBL237275 | 0.74 | ALOX15 (0.47) | ALOX15ALDH1A1TSHRKMT2ATDP1 | |
| SCHEMBL3363343 | 0.72 | — | — | |
| SCHEMBL15895051 | 0.72 | — | — | |
| SCHEMBL8967234 | 0.68 | ALOX15 (0.50) | ALOX15ALDH1A1TSHRKMT2ATDP1 | |
| SCHEMBL869608 | 0.68 | ALOX15 (0.42) | ALOX15ALDH1A1TSHR | |
| SCHEMBL5337690 | 0.68 | ALOX15 (0.37) | ALOX15ALDH1A1TSHR | |
| SCHEMBL3899877 | 0.68 | ALOX15 (0.41) | ALOX15ALDH1A1TSHRTDP1SRC | |
| SCHEMBL114337 | 0.68 | ALOX15 (0.55) | ALOX15ALDH1A1TSHRTDP1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276712-A2 | 2,6-DIAMINO-6-METHYL-HEPTANOIC ACID AND DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF | Degussa AG (DE) | 2003-01-22 | — | — | EP | disclosed |
| US-6504047-B2 | 2,6-diamino-6-methyl-heptanoic acid and derivatives as chemical intermediates useful for preperation of biological active compounds such as alpha-amino-epsilon caprolactam derivatives | DEGUSSA AG (DE) | 2003-01-07 | — | — | US | disclosed |
| US-20020016366-A1 | 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparation thereof and use thereof | DEGUSSA AG (DE) | 2002-02-07 | — | — | US | disclosed |
| WO-2001083423-A2 | 2,6-DIAMINO-6-METHYL-HEPTANOIC ACID AND DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF | DEGUSSA AG (DE) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016366-A1 | 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparation thereof and use thereof | CYP2D6, CYP2B6, CYP2A6 | ALOX15 322/4885ALDH1A1 18/4885TSHR 3873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.