Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899877 | 0.80 | ALOX15 (0.41) | ALOX15ALDH1A1TSHRSRCTDP1 | |
| SCHEMBL14331466 | 0.80 | ALOX15 (0.48) | ALOX15ALDH1A1TSHRSRCKMT2A | |
| SCHEMBL14323435 | 0.80 | ALOX15 (0.48) | ALOX15ALDH1A1TSHRSRCKMT2A | |
| SCHEMBL4867630 | 0.79 | ALOX15 (0.40) | ALOX15ALDH1A1TSHRSRCTDP1 | |
| SCHEMBL4866731 | 0.75 | ALOX15 (0.37) | ALOX15ALDH1A1TSHRUSP2TDP1 | |
| SCHEMBL11868741 | 0.75 | ALOX15 (0.52) | ALOX15ALDH1A1TSHRSRCKMT2A | |
| SCHEMBL11689424 | 0.74 | ALOX15 (0.47) | ALOX15ALDH1A1TSHRSRCKMT2A | |
| SCHEMBL7027334 | 0.74 | ALOX15 (0.42) | ALOX15ALDH1A1TSHRSRCKMT2A | |
| SCHEMBL3900721 | 0.74 | GLA (0.43) | ALOX15ALDH1A1TSHRKMT2ATDP1 | |
| SCHEMBL1532213 | 0.74 | FNTA (0.45) | ALOX15ALDH1A1KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346816-B1 | Chemically stable ingredients as lemon odorant | FIRMENICH & CIE (CH) | 2013-01-23 | — | — | EP | disclosed |
| US-8313736-B2 | Chemically stable ingredients as lemon odorant | FIRMENICH SA (CH) | 2012-11-20 | — | — | US | disclosed |
| US-20120003170-A1 | CHEMICALLY STABLE INGREDIENTS AS LEMON ODORANT | FIRMENICH SA (CH) | 2012-01-05 | — | — | US | disclosed |
| EP-2346816-A1 | CHEMICALLY STABLE INGREDIENTS AS LEMON ODORANT | Firmenich S.A. (CH) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010044031-A1 | CHEMICALLY STABLE INGREDIENTS AS LEMON ODORANT | FIRMENICH SA (CH) | 2010-04-22 | — | — | WO | disclosed |
| EP-1762565-B1 | Alkyl substituted octennitrile derivatives | INT FLAVORS & FRAGRANCES INC (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-1762565-B1 | Alkyl substituted octennitrile derivatives | INT FLAVORS & FRAGRANCES INC (US) | 2009-03-18 | — | — | EP | disclosed |
| US-7361630-B2 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANIES INC. (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361630-B2 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANIES INC. (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361630-B2 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANIES INC. (US) | 2008-04-22 | — | — | US | disclosed |
| EP-1762565-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-03-14 | — | — | EP | disclosed |
| EP-1762565-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-03-14 | — | — | EP | disclosed |
| US-20070055082-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-03-08 | — | — | US | disclosed |
| US-20070055082-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-03-08 | — | — | US | disclosed |
| US-20070055082-A1 | Alkyl substituted octennitrile derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-03-08 | — | — | US | disclosed |
| EP-0025939-B1 | ALIPHATIC METHOXY OR HYDROXY NITRILES, THEIR PREPARATION, AND THEIR USE AS ODORIFEROUS COMPOUNDS | BASF Aktiengesellschaft (DE) | 1982-05-26 | — | — | EP | disclosed |
| EP-0025939-A1 | Aliphatic methoxy or hydroxy nitriles, their preparation, and their use as odoriferous compounds | BASF Aktiengesellschaft (DE) | 1981-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070055082-A1 | Alkyl substituted octennitrile derivatives | ARNT, HCCS, AHR | ALOX15 1051/4885ALDH1A1 2282/4885TSHR 2221/4885 |
| US-20120003170-A1 | CHEMICALLY STABLE INGREDIENTS AS LEMON ODORANT | NISCH, TAS2R5, ODC1 | ALOX15 210/4885ALDH1A1 309/4885TSHR 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.