Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15895051 | 0.80 | — | — | |
| SCHEMBL3363343 | 0.80 | — | — | |
| SCHEMBL8327082 | 0.79 | ALOX15 (0.48) | ALOX15ALDH1A1TSHRSRCKMT2A | |
| SCHEMBL22241236 | 0.79 | ALOX15 (0.44) | ALOX15ALDH1A1TSHRSRCKMT2A | |
| SCHEMBL11868741 | 0.78 | ALOX15 (0.52) | ALOX15ALDH1A1TSHRSRCKMT2A | |
| SCHEMBL22111411 | 0.76 | ALOX15 (0.56) | ALOX15ALDH1A1TSHRSRCKMT2A | |
| SCHEMBL22111231 | 0.76 | ALOX15 (0.56) | ALOX15ALDH1A1TSHRSRCKMT2A | |
| SCHEMBL8468877 | 0.76 | ALOX15 (0.56) | ALOX15ALDH1A1TSHRSRCKMT2A | |
| SCHEMBL15880153 | 0.75 | GRIK1 (0.41) | ALOX15ALDH1A1TSHR | |
| SCHEMBL6488788 | 0.74 | ALOX15 (0.59) | ALOX15ALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523430-A | Protein farnesyl transferase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-06-04 | — | — | US | disclosed |