Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 2/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028357 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BKMT2AGAATSHR | |
| SCHEMBL7032233 | 0.85 | HDAC6 (0.54) | ITGB3ITGA2BKMT2ACYP2C19 | |
| SCHEMBL7033149 | 0.85 | HDAC6 (0.54) | ITGB3ITGA2BKMT2ACYP2C19 | |
| SCHEMBL7031835 | 0.82 | ITGB3 (0.66) | ITGB3ITGA2BKMT2ACYP2C19L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6700967 | 0.81 | ITGB3 (0.65) | ITGB3ITGA2BKMT2ACYP2C19L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7969479 | 0.81 | ITGB3 (0.65) | ITGB3ITGA2BKMT2ACYP2C19L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6700973 | 0.81 | ITGB3 (0.65) | ITGB3ITGA2BKMT2ACYP2C19L3MBTL1 | |
| SCHEMBL7032213 | 0.80 | ITGB3 (0.48) | ITGB3ITGA2BKMT2ACYP2C19MEN1 | |
| SCHEMBL7027895 | 0.80 | ITGB3 (0.48) | ITGB3ITGA2BKMT2ACYP2C19MEN1 | |
| SCHEMBL8475813 | 0.79 | MEN1 (0.48) | KMT2AGAATSHRCYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823898-B1 | HYDANTOINE DERIVATIVES AS INTERMEDIATE PRODUCTS FOR ACTIVE PHARMACEUTICAL AGENTS | HOECHST AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-5939556-A | Hydantoin compounds, salts thereof, processes for their preparation, and processes for preparing pharmaceutically active compounds comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |
| EP-0823898-A1 | HYDANTOINE DERIVATIVES AS INTERMEDIATE PRODUCTS FOR ACTIVE PHARMACEUTICAL AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996033976-A1 | HYDANTOINE DERIVATIVES AS INTERMEDIATE PRODUCTS FOR ACTIVE PHARMACEUTICAL AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-31 | — | — | WO | disclosed |