Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.44 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.44 |
| ▸ | F3 | P13726 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999708 | 0.84 | MAPT (0.58) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL1999706 | 0.84 | MAPT (0.58) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL1304550 | 0.80 | NFE2L2 (0.56) | ALDH1A1TSHRTRPA1MAOBNFE2L2 | |
| SCHEMBL1304546 | 0.80 | NFE2L2 (0.56) | ALDH1A1TSHRTRPA1MAOBNFE2L2 | |
| (Z)-1,2-Diphenylethene SCHEMBL10982590 | 0.80 | ALDH1A1 (0.57) | ALDH1A1TSHRTRPA1MAOBNFE2L2 | |
| (Z)-1,2-Diphenylethene SCHEMBL10982588 | 0.80 | ALDH1A1 (0.57) | ALDH1A1TSHRTRPA1MAOBNFE2L2 | |
| Cinnamic Acid SCHEMBL11333815 | 0.79 | HCAR2 (0.73) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL570817 | 0.78 | MAPT (0.52) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL17156438 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL3360362 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280832-A2 | CHAIN-COUPLED POLYMERIC ALKOXIDE COMPOUNDS HAVING CONTROLLED VISCOSITY | Bridgestone Corporation (JP) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001087993-A2 | CHAIN-COUPLED POLYMERIC ALKOXIDE COMPOUNDS HAVING CONTROLLED VISCOSITY | BRIDGESTONE CORPORATION (JP) | 2001-11-22 | — | — | WO | disclosed |