SCHEMBL7028186

SCHEMBL7028186

CCCCCCCCCC(CCCC)C(=O)Nc1cc[c]c(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.49
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HDAC8 Q9BY41 5/20 0.44
HDAC3 O15379 3/20 0.44
HDAC6 Q9UBN7 3/20 0.44
HDAC1 Q13547 3/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC4 P56524 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9812967 0.79 HDAC8 (0.54) LMNAMEN1ALDH1A1MAPTMAPK1
SCHEMBL7607420 0.77 RAB9A (0.56) LMNAALDH1A1MAPTMAPK1KMT2A
SCHEMBL6135037 0.77 ALDH1A1 (0.54) LMNAMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL18882713 0.76 MEN1 (0.72) LMNAMEN1ALDH1A1MAPTMAPK1
SCHEMBL15020945 0.76 MEN1 (0.61) LMNAMEN1ALDH1A1MAPTMAPK1
SCHEMBL9163890 0.75 HDAC8 (0.47) LMNAMEN1ALDH1A1MAPTMAPK1
SCHEMBL1525705 0.74 MEN1 (0.68) LMNAMEN1ALDH1A1MAPTMAPK1
SCHEMBL1525323 0.74 MEN1 (0.63) LMNAMEN1ALDH1A1MAPTMAPK1
SCHEMBL15021080 0.74 LMNA (0.68) LMNAMEN1ALDH1A1MAPTMAPK1
SCHEMBL23430657 0.74 MAPT (0.56) LMNAMEN1ALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0745894-B1 Black and white photographic elements containing release compounds and method of preparing photographic emulsion EASTMAN KODAK CO (US) 2003-01-22 EP disclosed
EP-0689092-B1 Photographic elements containing development accelerators and release compounds that release development inhibitors EASTMAN KODAK CO (US) 1998-01-14 EP disclosed
EP-0684512-B1 Photographic elements containing release compounds EASTMAN KODAK CO (US) 1997-12-17 EP disclosed
EP-0684513-B1 Photographic elements containing development accelerators and release compounds that release development inhibitors EASTMAN KODAK CO (US) 1997-07-23 EP disclosed
EP-0745894-A1 Black and white photographic elements containing release compounds and method of preparing photographic emulsion EASTMAN KODAK COMPANY (US) 1996-12-04 EP disclosed
US-5567577-A COMPRISING A BLOCKING GROUP FROM WHICH THE PHOTOGRAPHICALLY ACTIVE MOIETY IS RELEASED, A BALLASTING GROUP AND AN AQUEOUS SOLUBILIZING GROUP EASTMAN KODAK COMPANY (US) 1996-10-22 US disclosed
US-5500338-A Black and white photographic elements containing release compounds and method of preparing photographic emulsion EASTMAN KODAK COMPANY (US) 1996-03-19 US disclosed
EP-0689092-A1 Photographic elements containing development accelerators and release compounds that release development inhibitors EASTMAN KODAK COMPANY (US) 1995-12-27 EP disclosed
US-5478711-A Photographic elements containing development accelerators and release compounds that release development inhibitors EASTMAN KODAK COMPANY (US) 1995-12-26 US disclosed
EP-0684513-A1 Photographic elements containing development accelerators and release compounds that release development inhibitors EASTMAN KODAK COMPANY (US) 1995-11-29 EP disclosed
EP-0684512-A1 Photographic elements containing release compounds EASTMAN KODAK COMPANY (US) 1995-11-29 EP disclosed
US-5460932-A Controlling color balance EASTMAN KODAK COMPANY (US) 1995-10-24 US disclosed