Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10930927 | 0.84 | SLC6A4 (0.52) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL22579672 | 0.83 | SLC6A2 (0.65) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL6937427 | 0.82 | TRPA1 (0.38) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL10451794 | 0.81 | SLC6A4 (0.44) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL10451830 | 0.81 | SLC6A4 (0.44) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL10451793 | 0.81 | SLC6A4 (0.44) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL4373667 | 0.80 | OPRD1 (0.41) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL4663475 | 0.79 | OPRD1 (0.39) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL3992939 | 0.79 | ALDH1A1 (0.49) | SLC6A4SLC6A2OPRM1OPRK1MEN1 | |
| SCHEMBL3994483 | 0.79 | ALDH1A1 (0.49) | SLC6A4SLC6A2OPRM1OPRK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322590-A1 | 5-AMINO-1-PENTENE-3-OL SUBSTITUTED DERIVATIVES | Grünenthal GmbH (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002030869-A1 | 5-AMINO-1-PENTENE-3-OL SUBSTITUTED DERIVATIVES | Grünenthal GmbH (DE) | 2002-04-18 | — | — | WO | disclosed |