Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAK | O14976 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7031307 | 0.98 | GAA (0.33) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL7030432 | 0.84 | ALDH1A1 (0.35) | KDM4EALDH1A1MAPT | |
| SCHEMBL11608060 | 0.79 | LMNA (0.40) | KDM4EALDH1A1MAPTGAALMNA | |
| SCHEMBL7144640 | 0.79 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL11710424 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1MAPT | |
| SCHEMBL10549684 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL9802011 | 0.75 | NPSR1 (0.30) | — | |
| SCHEMBL11605697 | 0.73 | CACNA2D1 (0.31) | KDM4EALDH1A1MAPT | |
| SCHEMBL7031322 | 0.72 | LMNA (0.46) | KDM4EALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL7030321 | 0.71 | LMNA (0.45) | KDM4EALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889884-B1 | 1,2,4-TRIAZINE DERIVATIVES FOR THE INHIBITION OF PROTEIN GLYCOSYLATION | ALTEON INC (US) | 2003-01-29 | — | — | EP | claimed |
| EP-0889884-B1 | 1,2,4-TRIAZINE DERIVATIVES FOR THE INHIBITION OF PROTEIN GLYCOSYLATION | ALTEON INC (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6380192-B1 | FOR INHIBITING NONENZYMATIC CROSS-LINKING (PROTEIN AGING) | ALTEON, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6060470-A | Triazine compounds and methods of use therefor | ALTEON, INC. | 2000-05-09 | — | — | US | disclosed |
| US-5932578-A | CAPABLE OF INHIBITING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS OF TARGET PROTEINS. FOOD SPOILAGE AND ANIMAL PROTEIN AGING CAN BE TREATED. | ALTEON INC. (US) | 1999-08-03 | — | — | US | disclosed |