Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028529 | 1.00 | KMT2A (0.42) | KMT2AKCNH2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6742864 | 0.89 | KCNH2 (0.44) | KMT2AKCNH2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6989036 | 0.87 | KCNH2 (0.37) | KMT2AKCNH2ALDH1A1LMNA | |
| SCHEMBL7036600 | 0.87 | KCNH2 (0.37) | KMT2AKCNH2ALDH1A1LMNA | |
| SCHEMBL7034144 | 0.86 | CACNA1G (0.42) | KMT2AKCNH2ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7034146 | 0.86 | CACNA1G (0.42) | KMT2AKCNH2ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7028532 | 0.86 | KCNH2 (0.39) | KMT2AKCNH2ALDH1A1 | |
| SCHEMBL7033243 | 0.85 | KCNH2 (0.46) | KMT2AKCNH2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7033237 | 0.85 | KCNH2 (0.46) | KMT2AKCNH2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7028336 | 0.85 | KCNH2 (0.47) | KMT2AKCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212095-A1 | New bispidine compounds and their use in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212095-A1 | New bispidine compounds and their use in the treatment of cardiac arrhythmias | KCNH1, LBR, CACNA1E | KMT2A 2608/4885KCNH2 7/4885ALDH1A1 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.