Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | IAPP | P10997 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095910 | 0.97 | MAPT (0.36) | MAPTKMT2APLA2G2CIAPPCES2 | |
| SCHEMBL5705372 | 0.93 | MAPT (0.42) | MAPTKMT2APLA2G2CHAO1 | |
| SCHEMBL16799873 | 0.79 | MAPT (0.37) | MAPT | |
| SCHEMBL7103052 | 0.75 | — | — | |
| SCHEMBL7095906 | 0.75 | — | — | |
| SCHEMBL1286001 | 0.72 | L3MBTL1 (0.40) | KMT2A | |
| Acetic Acid SCHEMBL9277685 | 0.70 | GPR84 (0.45) | MAPT | |
| SCHEMBL19126676 | 0.68 | ALDH1A1 (0.46) | MAPTKMT2A | |
| SCHEMBL17228575 | 0.67 | CES1 (0.61) | MAPTKMT2ACES2CES1HAO1 | |
| SCHEMBL11166999 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030860-A9 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS INC (US) | 2003-02-20 | — | — | WO | disclosed |