Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727917 | 0.86 | GABRA1 (0.54) | HTR1DGABRA1GABRB2HTR1BPOLB | |
| SCHEMBL21553551 | 0.86 | HIF1A (0.46) | GABRA1GABRB2POLBTP53TSHR | |
| SCHEMBL20472890 | 0.83 | GABRA1 (0.50) | HTR1DGABRA1GABRB2HTR1BPOLB | |
| SCHEMBL28433211 | 0.80 | GABRA1 (0.48) | HTR1DGABRA1GABRB2HTR1BPOLB | |
| SCHEMBL29222655 | 0.80 | GABRA1 (0.48) | HTR1DGABRA1GABRB2HTR1BPOLB | |
| SCHEMBL28264683 | 0.76 | TACR1 (0.46) | HTR1DGABRA1GABRB2HTR1BPOLB | |
| SCHEMBL20582344 | 0.75 | GABRA1 (0.45) | HTR1DGABRA1GABRB2HTR1BTP53 | |
| SCHEMBL49284 | 0.72 | ALDH1A1 (0.54) | POLBTP53TSHRLMNACYP2D6 | |
| SCHEMBL8213794 | 0.72 | GABRA1 (0.50) | HTR1DGABRA1GABRB2HTR1BPOLB | |
| SCHEMBL1655430 | 0.72 | GABRA1 (0.55) | HTR1DGABRA1GABRB2HTR1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649874-B1 | Nucleation of crystallization in polyesters | M & G POLIMERI ITALIA SPA (IT) | 2003-01-22 | — | — | EP | disclosed |
| US-5641549-A | DUAL OVENABLE FOOD TRAYS | SHELL OIL COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| US-5431972-A | Polytetrafluoroethylene, linear low density polyethylene, stabilizer | SHELL OIL COMPANY (US) | 1995-07-11 | — | — | US | disclosed |
| EP-0649874-A2 | Nucleation of crystallization in polyesters | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-04-26 | — | — | EP | disclosed |
| EP-0044874-B1 | STABLE ANTI-FOULING PAINT COMPOSITION | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1983-08-03 | — | — | EP | disclosed |
| US-4376181-A | TRIORGANO-TIN POLYMER, CUPROUS OXIDE, HINDERED PHENOL | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1983-03-08 | — | — | US | disclosed |
| EP-0044874-A1 | STABLE ANTI-FOULING PAINT COMPOSITION | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1982-02-03 | — | — | EP | disclosed |
| US-4221700-A | POLY(ALKYLATED ALKENYLPHENOL); POLYESTERS OF ALKYLTHIOALKANOIC ACIDS OR ORGANIC PHOSPHITE | MARUZEN OIL CO., LTD. (JP) | 1980-09-09 | — | — | US | disclosed |