SCHEMBL28433211

SCHEMBL28433211

CC(C)(C)c1cc(Cc2cc(C(C)(C)C)cc(C(C)(C)C)c2)cc(C(C)(C)C)c1.[NaH]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
HMGCR P04035 3/20 0.40
POLB P06746 1/20 0.39
RXRA P19793 3/20 0.38
RXRB P28702 3/20 0.38
RXRG P48443 3/20 0.38
HTR1D P28221 3/20 0.38
CYP2C19 P33261 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
HTR1B P28222 2/20 0.34
TACR1 P25103 1/20 0.34
BCHE P06276 3/20 0.32
ACHE P22303 3/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20472890 0.97 GABRA1 (0.50) GABRA1GABRB2HMGCRPOLBRXRA
SCHEMBL29222655 0.94 GABRA1 (0.48) GABRA1GABRB2HMGCRPOLBRXRA
SCHEMBL28264683 0.84 TACR1 (0.46) GABRA1GABRB2HMGCRPOLBRXRA
Phosphoric Acid SCHEMBL30100628 0.84 HMGCR (0.46) GABRA1GABRB2HMGCRRXRARXRB
SCHEMBL27273119 0.84 CALM1 (0.52) GABRA1GABRB2RXRARXRBRXRG
SCHEMBL30468716 0.82 HSPA5 (0.42) GABRA1GABRB2HMGCRPOLBRXRA
SCHEMBL887683 0.82 GABRA1 (0.38) GABRA1GABRB2HMGCRPOLBRXRA
Phosphoric Acid SCHEMBL27844801 0.82 HMGCR (0.45) GABRA1GABRB2HMGCRPOLBRXRA
SCHEMBL7028595 0.80 HTR1D (0.42) GABRA1GABRB2HMGCRPOLBRXRA
SCHEMBL12205267 0.80 ALDH1A1 (0.53) GABRA1GABRB2POLBCYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113518796-B Process for preparing heterophasic polymer compositions 美利肯公司 2023-06-23 CN claimed
CN-113518796-B Process for preparing heterophasic polymer compositions 美利肯公司 2023-06-23 CN disclosed
CN-110072932-B Additive composition and method of use 美利肯公司 2022-01-25 CN disclosed
CN-113518796-A Process for preparing a heterophasic polymer composition 美利肯公司 2021-10-19 CN disclosed
CN-112739773-A Thermoplastic compositions having improved toughness, articles made therefrom, and methods thereof 布拉斯科美国有限责任公司 2021-04-30 CN disclosed
CN-111511830-A Polyolefins with improved dimensional stability in three-dimensional printing, articles formed therefrom, and methods thereof 布拉斯科有限公司 2020-08-07 CN disclosed