Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 7/20 | 0.49 |
| ▸ | CHUK | O15111 | 6/20 | 0.49 |
| ▸ | PRKCI | P41743 | 3/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776911 | 0.80 | PRKCI (0.42) | IKBKBCHUKPRKCIAXLNUDT1 | |
| SCHEMBL30353820 | 0.80 | PRKCI (0.42) | IKBKBCHUKPRKCIAXLNUDT1 | |
| SCHEMBL27634823 | 0.80 | PRKCI (0.42) | IKBKBCHUKPRKCIAXLNUDT1 | |
| SCHEMBL29424797 | 0.78 | BRD4 (0.60) | IKBKBCHUKPRKCIAXLNUDT1 | |
| SCHEMBL298491 | 0.78 | BRD4 (0.60) | IKBKBCHUKPRKCIAXLNUDT1 | |
| SCHEMBL12605417 | 0.76 | IKBKB (0.45) | IKBKBCHUKPRKCIAXLNUDT1 | |
| SCHEMBL28028675 | 0.75 | IKBKB (0.52) | IKBKBCHUKPRKCIAXLNUDT1 | |
| SCHEMBL2992617 | 0.75 | NUDT1 (0.55) | IKBKBCHUKPRKCIAXLNUDT1 | |
| SCHEMBL27616079 | 0.74 | NUDT1 (0.51) | IKBKBCHUKPRKCIAXLNUDT1 | |
| SCHEMBL2986157 | 0.73 | CIT (0.50) | IKBKBCHUKPRKCIAXLNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397360-A1 | AZAINDOLES | Aventis Pharma Limited (GB) | 2004-03-17 | — | — | EP | disclosed |
| WO-2003000688-A1 | AZAINDOLES | AVENTIS PHARMA LIMITED (GB) | 2003-01-03 | — | — | WO | disclosed |