Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.68 |
| ▸ | CTSB | P07858 | 6/20 | 0.68 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.67 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.67 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.67 |
| ▸ | CTSK | P43235 | 4/20 | 0.62 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028811 | 1.00 | CTSL (0.68) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL14341576 | 0.96 | CTSL (0.73) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL23234553 | 0.96 | CTSL (0.73) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL2253238 | 0.96 | CTSL (0.73) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL8260303 | 0.96 | CTSL (0.73) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL8259974 | 0.95 | CTSL (0.71) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL2141126 | 0.95 | CTSL (0.71) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL29434595 | 0.94 | CTSB (0.62) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL7028199 | 0.90 | CTSL (0.65) | CTSLCTSB | |
| SCHEMBL14513407 | 0.90 | CTSL (0.65) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002048097-A9 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF PARASITIC INFECTIONS | CORVAS INT INC (US) | 2003-05-08 | — | — | WO | disclosed |
| US-20020107266-A1 | Compounds, compositions and methods for treatment of parasitic infections | DENDREON CORPORATION | 2002-08-08 | — | — | US | disclosed |
| WO-2002048097-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF PARASITIC INFECTIONS | CORVAS INTERNATIONAL, INC. (US) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107266-A1 | Compounds, compositions and methods for treatment of parasitic infections | CAT, CTSA, CTRL | CTSL 26/4885CTSB 6/4885PSMB1 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.