SCHEMBL702892

SCHEMBL702892

COc1ccc2ccc(C3CCCS3)cc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
CYP2A6 P11509 1/20 0.43
MAOA P21397 1/20 0.42
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
MAP2K1 Q02750 1/20 0.39
RAB9A P51151 1/20 0.39
HTR1A P08908 1/20 0.38
HTR1D P28221 1/20 0.38
HTR1B P28222 1/20 0.38
FDFT1 P37268 1/20 0.36
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
F2R P25116 1/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP17A1 P05093 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27621080 0.97 MAOA (0.44) CYP1A2CYP2A6MAOASLC6A2SLC6A4
SCHEMBL703410 0.85 MAOA (0.46) CYP1A2MAOASLC6A2SLC6A4RAB9A
SCHEMBL9359327 0.82 MAOA (0.58) MAOASLC6A2SLC6A4SLC6A3MAP2K1
SCHEMBL700280 0.82 MAOA (0.48) CYP1A2MAOAMAPK1TSHR
SCHEMBL701986 0.82 MAOA (0.48) MAOA
SCHEMBL27639889 0.81 KDM4E (0.46) MAOASLC6A2SLC6A4SLC6A3
SCHEMBL27621112 0.79 MAOB (0.40) MAOATSHR
SCHEMBL27639854 0.79 MAOA (0.50) MAOARAB9A
SCHEMBL29576576 0.78 TSHR (0.51) CYP1A2CYP2A6MAOASLC6A2SLC6A4
SCHEMBL11086094 0.78 TSHR (0.51) CYP1A2CYP2A6MAOASLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325694-B1 RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST PATTERN FORMATION METHOD JSR CORP (JP) 2017-11-08 EP disclosed
US-20120164586-A1 PATERN FORMING METHOD JSR CORPORATION (JP) 2012-06-28 US disclosed
US-8124314-B2 Radiation-sensitive composition JSR CORPORATION (JP) 2012-02-28 US disclosed
US-20110262865-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND POLYMER JSR CORPORATION (JP) 2011-10-27 US disclosed
US-20110212401-A1 RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST PATTERN FORMATION METHOD JSR CORPORATION (JP) 2011-09-01 US disclosed
EP-2325694-A1 RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST PATTERN FORMATION METHOD JSR Corporation (JP) 2011-05-25 EP disclosed
US-20100221664-A1 RADIATION-SENSITIVE COMPOSITION JSR CORPORATION (JP) 2010-09-02 US disclosed
US-20100203452-A1 RADIATION-SENSITIVE COMPOSITION JSR CORPORATION (JP) 2010-08-12 US disclosed