SCHEMBL7029015

SCHEMBL7029015

CCCCCC1CCC(c2ccc(-c3ccc(CCCO)c(F)c3)cc2)CC1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.39
SPHK1 Q9NYA1 6/20 0.38
CYP2C9 P11712 1/20 0.38
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36
CA2 P00918 1/20 0.36
RARB P10826 2/20 0.36
RARA P10276 1/20 0.36
RARG P13631 1/20 0.36
FFAR4 Q5NUL3 1/20 0.35
DGAT1 O75907 2/20 0.35
SOAT1 P35610 1/20 0.35
P2RY14 Q15391 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026576 0.94 ESR2 (0.40) ESR2SPHK1CYP2C9ALDH1A1LMNA
SCHEMBL7027476 0.93 CYP2C9 (0.44) ESR2SPHK1CYP2C9ALDH1A1LMNA
SCHEMBL7028254 0.89 CA2 (0.39) ESR2SPHK1CYP2C9ALDH1A1CA2
SCHEMBL7034701 0.88 ESR2 (0.37) ESR2SPHK1CYP2C9ALDH1A1LMNA
SCHEMBL7031720 0.88 ESR2 (0.40) ESR2SPHK1CYP2C9ALDH1A1LMNA
SCHEMBL20903897 0.87 SPHK1 (0.43) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8449020 0.87 CYP2C9 (0.41) ESR2SPHK1CYP2C9ALDH1A1LMNA
SCHEMBL8449025 0.87 CYP2C9 (0.41) ESR2SPHK1CYP2C9ALDH1A1LMNA
SCHEMBL19722562 0.87 MAPT (0.35) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL7031164 0.86 CYP2C9 (0.46) ESR2SPHK1CYP2C9ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 US disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 US disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 US disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 EP disclosed
EP-0754668-B1 Fluorobenzylether derivatives ROLIC AG (CH) 2003-02-05 EP disclosed
EP-0754668-A2 Fluorobenzylether derivatives Rolic AG (CH) 1997-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 ESR2 2127/4885SPHK1 435/4885CYP2C9 4226/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 ESR2 2096/4885SPHK1 646/4885CYP2C9 4442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.