Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029497 | 1.00 | GPR119 (0.34) | GPR119LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27612774 | 0.84 | GPR119 (0.36) | GPR119LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6881805 | 0.76 | HDAC4 (0.37) | P2RX7 | |
| SCHEMBL6881811 | 0.76 | HDAC4 (0.37) | P2RX7 | |
| SCHEMBL6881809 | 0.76 | HDAC4 (0.37) | P2RX7 | |
| SCHEMBL17051575 | 0.74 | NPC1 (0.44) | GPR119LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6854227 | 0.72 | ALDH1A1 (0.39) | GPR119LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6854224 | 0.72 | ALDH1A1 (0.39) | GPR119LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL12970083 | 0.72 | FYN (0.41) | LMNASMN1; SMN2NPC1RAB9ANFKB1 | |
| SCHEMBL6850714 | 0.72 | MEN1 (0.38) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |