Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31081384 | 0.80 | ALDH1A1 (0.59) | ALDH1A1GAAPOLBKMT2AMEN1 | |
| SCHEMBL5085548 | 0.80 | ALDH1A1 (0.59) | ALDH1A1GAAPOLBKMT2AMEN1 | |
| SCHEMBL379054 | 0.72 | ALDH1A1 (0.67) | ALDH1A1POLBTHRBKMT2AMEN1 | |
| SCHEMBL3504905 | 0.72 | ALDH2 (0.47) | ALDH1A1ALDH2ALDH3A1KDM4E | |
| SCHEMBL5084426 | 0.70 | AKR1B1 (0.69) | ALDH1A1GAAPOLBTHRBKMT2A | |
| SCHEMBL6190746 | 0.69 | ALDH1A1 (0.66) | ALDH1A1POLBAKR1B1KDM4EUSP2 | |
| SCHEMBL5559080 | 0.69 | POLB (0.59) | ALDH1A1POLBTHRBKMT2AMEN1 | |
| SCHEMBL7030775 | 0.67 | ALDH2 (0.53) | ALDH1A1ALDH2ALDH3A1THRBKMT2A | |
| SCHEMBL22617287 | 0.65 | MAOB (0.68) | GAAPOLBTHRBKMT2AMEN1 | |
| SCHEMBL6331018 | 0.65 | ALDH1A1 (0.59) | ALDH1A1AKR1B1KDM4EUSP2CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322308-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | Durect Corporation (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002028366-A9 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORP (US) | 2003-02-13 | — | — | WO | disclosed |
| WO-2002028366-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |