SCHEMBL7029618

SCHEMBL7029618

CCCOC(=O)c1scc(CC)c1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
KDM4E B2RXH2 3/20 0.43
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 7/20 0.42
LMNA P02545 2/20 0.41
TSHR P16473 2/20 0.40
ESR1 P03372 1/20 0.40
CHRM1 P11229 1/20 0.40
SLC6A2 P23975 1/20 0.40
KDR P35968 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
POLB P06746 2/20 0.38
MAPK1 P28482 1/20 0.38
GRM6 O15303 1/20 0.38
GLA P06280 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7028068 0.98 MAPT (0.44) MAPTKDM4EKMT2AALDH1A1LMNA
SCHEMBL7033145 0.87 ALDH1A1 (0.50) MAPTKDM4EKMT2AALDH1A1LMNA
Hydrochloric Acid SCHEMBL7023204 0.85 ALDH1A1 (0.50) MAPTKDM4EKMT2AALDH1A1LMNA
SCHEMBL7028009 0.84 MAPT (0.49) MAPTKDM4EKMT2AALDH1A1LMNA
Hydrochloric Acid SCHEMBL7035047 0.83 MAPT (0.48) MAPTKDM4EKMT2AALDH1A1LMNA
SCHEMBL7026692 0.83 MAPT (0.44) MAPTKDM4EKMT2AALDH1A1LMNA
SCHEMBL7688016 0.81 KDM4E (0.57) MAPTKDM4EKMT2AALDH1A1NPC1
Hydrochloric Acid SCHEMBL7033082 0.81 MAPT (0.43) MAPTKDM4EKMT2AALDH1A1LMNA
SCHEMBL7030242 0.79 CA2 (0.43) MAPTKDM4EKMT2AALDH1A1LMNA
SCHEMBL7031055 0.79 MAPT (0.42) MAPTKDM4EKMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1232505-C Substituted sulfonamido (thio) carbonyl compounds BAYER AG (DE) 2005-12-21 CN disclosed
CN-1439631-A Substituted sulfonamido (thio) carbonyl compounds BAYER AG (DE) 2003-09-03 CN disclosed
US-20030162979-A1 Substituted sulphonylamino(thio)carbonyl compounds MULLER KLAUS-HELMUT (DE) 2003-08-28 US disclosed
CN-1105717-C Substituted sulfonamido (thio) carbonyl compounds BAYER AG (DE) 2003-04-16 CN disclosed
US-6441195-B1 2-ALKOXYCARBONYL-3-SULPHONAMIDE, SULPHONYL ISOCYANATE OR SULPHONYL ISOTHIOCYANATE-THIOPHENES; PRE- OR POSTEMERGENCE HERBICIDES; EFFICIENCY BAYER AKTIENGESELLSCHAFT (DE) 2002-08-27 US disclosed
US-6180567-B1 REACTING 2-ALKOXYCARBONYL-BENZENESULFONAMIDE DERIVATIVE WITH 1,2,4-(1H)TRIAZOLE-5-(THI)ONE DERIVATIVE BAYER AKTIENGESELLSCHAFT (DE) 2001-01-30 US disclosed
CN-1207099-A Substituted sulfonamido (thio) carbonyl compounds BAYER AG (DE) 1999-02-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162979-A1 Substituted sulphonylamino(thio)carbonyl compounds CBR3, CTH, CBR1 MAPT 4635/4885KDM4E 2583/4885KMT2A 2161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.