Crotonic Acid

Crotonic Acid

SCHEMBL7029699

C/C=C/C(=O)O.C=CC(C)C(=O)O.C=CCC(=O)O

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565012 0.88 CYP2D6 (0.35)
Crotonic Acid SCHEMBL2406680 0.86 ALOX15 (0.36)
Crotonic Acid SCHEMBL11525007 0.86 ALOX15 (0.36)
Crotonic Acid SCHEMBL1618932 0.86 ALOX15 (0.36)
Crotonic Acid SCHEMBL27396103 0.80 FFAR3 (0.40)
Maleic Acid SCHEMBL3703143 0.73 TSHR (0.50)
Fumaric Acid SCHEMBL4979324 0.73 TSHR (0.50)
Fumaric Acid SCHEMBL3703148 0.73 TSHR (0.50)
SCHEMBL22624 0.73
SCHEMBL14691575 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0983040-B1 HAIR FIXING COMPOSITION COLGATE PALMOLIVE CO (US) 2003-01-15 EP disclosed
EP-0983040-A1 HAIR FIXING COMPOSITION Colgate-Palmolive Company (a Delaware corporation) (US) 2000-03-08 EP disclosed
WO-1998052517-A1 HAIR FIXING COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 1998-11-26 WO disclosed
WO-1998038972-A1 HAIR FIXING COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 1998-09-11 WO disclosed
US-5702692-A HAIR SPRAY COMPRISING VINYL ACETATE-VINYLPYRROLIDONE COPOLYMER, NEUTRALIZED TERPOLYMER OF TERTIARY-BUTYL ACRYLATE, ETHYL ACRYLATE, METHACRYLIC ACID IN COMPATIBLE SOLVENT SYSTEM COLGATE-PALMOLIVE COMPANY (US) 1997-12-30 US disclosed