Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 9/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024851 | 0.92 | RARB (0.41) | GPR84RARBRARARARGNAAA | |
| SCHEMBL8219129 | 0.88 | RARB (0.34) | GPR84RARBRARARARGMAOA | |
| SCHEMBL8215809 | 0.88 | RARB (0.34) | GPR84RARBRARARARGMAOA | |
| SCHEMBL7030009 | 0.86 | GPR84 (0.38) | GPR84RARBRARARARGNAAA | |
| SCHEMBL8390142 | 0.86 | HTR2A (0.34) | MAOAMAOB | |
| SCHEMBL7025174 | 0.86 | HTR2A (0.34) | MAOAMAOB | |
| SCHEMBL7021186 | 0.86 | GPR84 (0.35) | GPR84NAAAFAAH | |
| SCHEMBL7031162 | 0.85 | CYP2C9 (0.43) | NAAAFAAH | |
| SCHEMBL7030006 | 0.84 | RARB (0.39) | GPR84RARBRARARARGMAOA | |
| SCHEMBL10345128 | 0.83 | CYP17A1 (0.42) | GPR84RARBRARARARGMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |