Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024857 | 0.92 | RARB (0.44) | RARBRARARARGGPR84KIF11 | |
| SCHEMBL7031164 | 0.86 | CYP2C9 (0.46) | FFAR4 | |
| SCHEMBL7025178 | 0.86 | HTR2A (0.37) | GPR84S1PR1MAOAMAOBHTR2A | |
| SCHEMBL7030011 | 0.86 | GPR84 (0.39) | RARBRARARARGGPR84KIF11 | |
| SCHEMBL8219129 | 0.84 | RARB (0.34) | RARBRARARARGGPR84MAOA | |
| SCHEMBL8215809 | 0.84 | RARB (0.34) | RARBRARARARGGPR84MAOA | |
| SCHEMBL7021187 | 0.84 | KIF11 (0.36) | RARBRARARARGGPR84KIF11 | |
| SCHEMBL10345128 | 0.84 | CYP17A1 (0.42) | RARBRARARARGGPR84KIF11 | |
| SCHEMBL7030005 | 0.84 | GPR84 (0.38) | RARBRARARARGGPR84MAOA | |
| SCHEMBL7902474 | 0.83 | HTR2A (0.37) | RARBRARARARGGPR84MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |