SCHEMBL7030188

SCHEMBL7030188

CCOC(=O)C1SCC(C)C1=NO

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.33
GLA P06280 1/20 0.33
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 2/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PPM1B O75688 1/20 0.30
PTPN1 P18031 1/20 0.30
PPP1CC P36873 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7030167 0.88 PPM1B (0.33) PPM1BPTPN1PPP1CC
SCHEMBL7033442 0.88 PPM1B (0.33) PPM1BPTPN1PPP1CC
SCHEMBL7028090 0.83 KDM4E (0.33) KDM4EGLAMEN1ALDH1A1KMT2A
SCHEMBL7029365 0.83 KDM4E (0.33) KDM4EGLAMEN1ALDH1A1KMT2A
SCHEMBL7028055 0.80 PKM (0.33) KDM4EMEN1ALDH1A1KMT2AMAPT
SCHEMBL7034548 0.79 KDM4E (0.38) KDM4EMEN1ALDH1A1KMT2AMAPT
SCHEMBL7027869 0.72 MMP2 (0.33) PPM1BPTPN1PPP1CC
SCHEMBL7029774 0.72 PPM1B (0.33) PPM1BPTPN1PPP1CC
SCHEMBL7029772 0.72 PPM1B (0.33) PPM1BPTPN1PPP1CC
SCHEMBL7025920 0.69 PPM1B (0.33) PPM1BPTPN1PPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030162979-A1 Substituted sulphonylamino(thio)carbonyl compounds MULLER KLAUS-HELMUT (DE) 2003-08-28 US disclosed
US-6441195-B1 2-ALKOXYCARBONYL-3-SULPHONAMIDE, SULPHONYL ISOCYANATE OR SULPHONYL ISOTHIOCYANATE-THIOPHENES; PRE- OR POSTEMERGENCE HERBICIDES; EFFICIENCY BAYER AKTIENGESELLSCHAFT (DE) 2002-08-27 US disclosed
US-6180567-B1 REACTING 2-ALKOXYCARBONYL-BENZENESULFONAMIDE DERIVATIVE WITH 1,2,4-(1H)TRIAZOLE-5-(THI)ONE DERIVATIVE BAYER AKTIENGESELLSCHAFT (DE) 2001-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162979-A1 Substituted sulphonylamino(thio)carbonyl compounds CBR3, CTH, CBR1 KDM4E 2583/4885GLA 4165/4885MEN1 4546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.