Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032708 | 0.76 | FOLH1 (0.44) | FDPS | |
| SCHEMBL9176133 | 0.74 | FDPS (0.54) | FDPS | |
| SCHEMBL21611867 | 0.69 | FOLH1 (0.59) | FDPS | |
| SCHEMBL3469956 | 0.68 | TYMS (0.55) | — | |
| SCHEMBL2321372 | 0.66 | FDPS (0.70) | FDPS | |
| SCHEMBL20699855 | 0.66 | FDPS (0.75) | FDPS | |
| SCHEMBL15305182 | 0.66 | TYMS (0.52) | — | |
| SCHEMBL8198270 | 0.65 | KDM4E (0.56) | FDPS | |
| SCHEMBL18526938 | 0.65 | PAOX (0.42) | FDPS | |
| SCHEMBL6422244 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131327-B1 | PROSTAGLANDIN CONJUGATES FOR TREATING OR PREVENTING BONE DISEASES | MERCK FROSST CANADA INC (CA) | 2003-02-19 | — | — | EP | disclosed |
| EP-1131327-A1 | PROSTAGLANDIN CONJUGATES FOR TREATING OR PREVENTING BONE DISEASE | Merck Frosst Canada & Co. (CA) | 2001-09-12 | — | — | EP | disclosed |
| US-6121253-A | BONE GROWTH-ENHANCING PROSTAGLANDIN DERIVATIVE CONTAINING BISPHOSPHONATE GROUPS TO INHIBIT BONE RESORPTION; DRUG DELIVERY, SIDE EFFECT REDUCTION, OSTEOPOROSIS | MERCK FROSST CANADA & CO. (CA) | 2000-09-19 | — | — | US | disclosed |
| WO-2000031084-A1 | PROSTAGLANDIN CONJUGATES FOR TREATING OR PREVENTING BONE DISEASE | MERCK FROSST CANADA & CO. (CA) | 2000-06-02 | — | — | WO | disclosed |