Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 7/20 | 0.54 |
| ▸ | THRB | P10828 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061230 | 0.89 | POLB (0.45) | THRATHRBNPC1POLBMMP13 | |
| SCHEMBL6660237 | 0.87 | THRA (0.52) | THRATHRBNPC1POLB | |
| SCHEMBL1641086 | 0.86 | THRB (0.48) | THRATHRBNPC1POLB | |
| SCHEMBL7061486 | 0.85 | THRA (0.46) | THRATHRBNPC1POLB | |
| SCHEMBL6738556 | 0.85 | THRB (0.57) | THRATHRBNPC1 | |
| SCHEMBL4965036 | 0.85 | THRB (0.46) | THRATHRBNPC1POLBMMP13 | |
| SCHEMBL6660048 | 0.84 | THRA (0.51) | THRATHRBNPC1POLBMMP13 | |
| SCHEMBL4961880 | 0.84 | THRB (0.49) | THRATHRBNPC1POLBMMP13 | |
| SCHEMBL6676555 | 0.84 | THRB (0.53) | THRATHRBNPC1POLB | |
| SCHEMBL7063024 | 0.83 | THRB (0.53) | THRATHRBNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555580-B2 | Treating arteriosclerosis and hypercholesterolaemia | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-29 | — | — | US | disclosed |
| US-20030027862-A1 | Amino-and amido-diphenyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027862-A1 | Amino-and amido-diphenyl ethers | APOB, DAO, DNPEP | THRA 2763/4885THRB 1856/4885NPC1 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.