SCHEMBL7030711

SCHEMBL7030711

CCS(=O)(=O)NC(=O)Nc1ccccc1P(=O)(OC(C)(C)C)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 1/20 0.36
GAA P10253 1/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MRGPRX1 Q96LB2 6/20 0.33
LMNA P02545 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6330219 0.82 MEN1 (0.36) CA1CA2L3MBTL1LMNAMEN1
SCHEMBL6323776 0.80 L3MBTL1 (0.42) GAACA1CA2L3MBTL1MRGPRX1
SCHEMBL6324268 0.75 CA1 (0.41) NLRP3GAACA1CA2L3MBTL1
SCHEMBL6325457 0.70 MRGPRX1 (0.41) MRGPRX1LMNAMEN1KMT2AMAPT
SCHEMBL6324608 0.69 POLB (0.43) CA1CA2LMNAMEN1KMT2A
SCHEMBL6465979 0.69 EPHX1 (0.62) NLRP3GAAMEN1KMT2AALDH1A1
SCHEMBL6330059 0.69 NLRP3 (0.38) NLRP3GAACA1CA2L3MBTL1
SCHEMBL5950437 0.68 POLB (0.57) L3MBTL1LMNAMEN1KMT2AALDH1A1
SCHEMBL27496346 0.67 AKR1B1 (0.44) L3MBTL1MEN1KMT2A
SCHEMBL6326462 0.67 MEN1 (0.40) GAAL3MBTL1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed