Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.61 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | MST1R | Q04912 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166037 | 0.97 | MET (0.64) | METFLT3KDR | |
| Trifluoroacetic Acid SCHEMBL697610 | 0.90 | MET (0.59) | METKDRMST1R | |
| Trifluoroacetic Acid SCHEMBL698719 | 0.87 | MET (0.70) | METFLT3KDR | |
| SCHEMBL168714 | 0.86 | MET (0.63) | METKDRMST1R | |
| SCHEMBL698255 | 0.84 | MET (0.74) | METFLT3KDR | |
| Trifluoroacetic Acid SCHEMBL695927 | 0.84 | MET (0.59) | METFLT3KDRMST1R | |
| SCHEMBL168462 | 0.82 | MET (0.63) | METFLT3 | |
| SCHEMBL167642 | 0.81 | MET (0.62) | METFLT3KDRMST1R | |
| SCHEMBL17370941 | 0.81 | MET (0.71) | METFLT3KDR | |
| SCHEMBL371608 | 0.80 | MET (0.68) | METFLT3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609091-B1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS AXL INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2014-11-26 | — | — | EP | disclosed |
| EP-2423208-A1 | Pharmaceutically active compounds as Axl inhibitors | Lead Discovery Center GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |