Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7031332 | 1.00 | TSHR (0.47) | TSHRNPSR1POLBKMT2AMEN1 | |
| SCHEMBL8059582 | 0.91 | NPSR1 (0.44) | TSHRNPSR1POLBKMT2AMEN1 | |
| SCHEMBL7038814 | 0.77 | LMNA (0.50) | POLBKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7038815 | 0.77 | LMNA (0.50) | POLBKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL11671207 | 0.73 | NPSR1 (0.67) | TSHRNPSR1POLBKMT2AMEN1 | |
| SCHEMBL3462834 | 0.73 | NPSR1 (0.67) | TSHRNPSR1POLBKMT2AMEN1 | |
| SCHEMBL11670786 | 0.70 | NPSR1 (0.70) | TSHRNPSR1POLBKMT2AMEN1 | |
| SCHEMBL11670709 | 0.70 | TSHR (0.71) | TSHRNPSR1POLBKMT2AMEN1 | |
| SCHEMBL7039189 | 0.70 | PLA2G2A (0.36) | KMT2AGPBAR1 | |
| SCHEMBL8055091 | 0.69 | TSHR (0.46) | TSHRNPSR1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225302-A1 | Aromatic amides, their preparation process and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2003-12-04 | — | — | US | claimed |
| US-20020068838-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 2002-06-06 | — | — | US | claimed |
| EP-1003714-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 2000-05-31 | — | — | EP | claimed |
| WO-1999001422-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1999-01-14 | — | — | WO | claimed |
| US-20030225302-A1 | Aromatic amides, their preparation process and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068838-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | CBR1, CBR3, CYP2E1 | TSHR 331/4885NPSR1 2331/4885POLB 3707/4885 |
| US-20030225302-A1 | Aromatic amides, their preparation process and their use as pesticides | CBR3, CBR1, CYP2E1 | TSHR 140/4885NPSR1 1748/4885POLB 3491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.