SCHEMBL7039189

SCHEMBL7039189

Cc1ccccc1-c1cc(CC(F)=Cc2ccc(Cl)c(Cl)c2)ccc1C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.36
PLA2G10 O15496 2/20 0.36
EIF4E P06730 2/20 0.35
GPR183 P32249 1/20 0.34
CD38 P28907 1/20 0.34
PIK3CA P42336 1/20 0.33
GPBAR1 Q8TDU6 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
TACR1 P25103 1/20 0.32
PDK2 Q15119 1/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
CCR2 P41597 1/20 0.32
ADRA1D P25100 1/20 0.32
PARP14 Q460N5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7599401 0.75 RORC (0.44) KMT2A
SCHEMBL7038814 0.72 LMNA (0.50) KMT2A
SCHEMBL7038815 0.72 LMNA (0.50) KMT2A
SCHEMBL7577374 0.72 BCAT2 (0.45) PLA2G2APLA2G10
SCHEMBL7031332 0.70 TSHR (0.47) GPBAR1KMT2A
SCHEMBL7031329 0.70 TSHR (0.47) GPBAR1KMT2A
SCHEMBL1788703 0.67 BCAT2 (0.59) KMT2A
SCHEMBL7890739 0.65 ALDH1A1 (0.46) KMT2A
SCHEMBL7575815 0.65 FNTA (0.39) PLA2G2APLA2G10FNTAFNTB
SCHEMBL13561160 0.63 PIK3CA (0.57) PIK3CAKMT2ASLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030225302-A1 Aromatic amides, their preparation process and their use as pesticides HOECHST SCHERING AGREVO S.A. (FR) 2003-12-04 US disclosed
US-20020068838-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 2002-06-06 US disclosed
EP-1003714-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES Hoechst Schering AgrEvo S.A. (FR) 2000-05-31 EP disclosed
WO-1999001422-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 1999-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020068838-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES CBR1, CBR3, CYP2E1 PLA2G2A 2553/4885PLA2G10 3218/4885EIF4E 3886/4885
US-20030225302-A1 Aromatic amides, their preparation process and their use as pesticides CBR3, CBR1, CYP2E1 PLA2G2A 3408/4885PLA2G10 3820/4885EIF4E 3989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.