Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.41 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31533316 | 0.91 | RXFP1 (0.51) | RXFP1P2RX3P2RX4 | |
| SCHEMBL7039480 | 0.91 | RXFP1 (0.51) | RXFP1P2RX3P2RX4 | |
| SCHEMBL7036534 | 0.80 | RXFP1 (0.46) | RXFP1P2RX3P2RX4TP53 | |
| SCHEMBL7037427 | 0.77 | RXFP1 (0.51) | RXFP1P2RY12P2RX3P2RX4 | |
| SCHEMBL31533317 | 0.76 | RXFP1 (0.53) | RXFP1P2RX3P2RX4 | |
| SCHEMBL30239003 | 0.75 | RXFP1 (0.43) | RXFP1NPEPPSP2RX3P2RX4 | |
| SCHEMBL14005578 | 0.74 | RXFP1 (0.47) | RXFP1P2RY12P2RX3P2RX4 | |
| SCHEMBL23120402 | 0.74 | PI4KA (0.43) | RXFP1P2RY12P2RX3P2RX4 | |
| SCHEMBL23120397 | 0.74 | PI4KA (0.43) | RXFP1P2RY12P2RX3P2RX4 | |
| SCHEMBL7037167 | 0.74 | RXFP1 (0.56) | RXFP1P2RY12P2RX3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991412-B1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARM INC (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5824657-A | ANTICARCINOGENIC AGENTS, SKIN DISORDERS AND PSORIASIS | CUBIST PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |