SCHEMBL7032023

SCHEMBL7032023

O=C(c1cccc(Cl)c1Cl)c1cccc(Cl)c1Cl

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.71
P2RX7 Q99572 1/20 0.58
ERCC5 P28715 1/20 0.55
FEN1 P39748 1/20 0.55
PKM P14618 5/20 0.53
ALDH1A1 P00352 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
CYP2C9 P11712 1/20 0.51
JAK2 O60674 1/20 0.50
TAS1R3 Q7RTX0 1/20 0.50
TAS1R1 Q7RTX1 1/20 0.50
TAS1R2 Q8TE23 1/20 0.50
HTT P42858 1/20 0.49
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
POLB P06746 1/20 0.46
RECQL P46063 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9134364 0.95 TSHR (0.65) TSHRP2RX7ERCC5FEN1PKM
SCHEMBL8606571 0.93 TSHR (0.63) TSHRP2RX7ERCC5FEN1PKM
SCHEMBL11013962 0.86 PKM (0.55) TSHRP2RX7ERCC5FEN1PKM
SCHEMBL8757108 0.86 TSHR (0.55) TSHRP2RX7ERCC5FEN1PKM
SCHEMBL30403796 0.85 TSHR (0.64) TSHRP2RX7ERCC5FEN1PKM
SCHEMBL334531 0.85 TSHR (0.64) TSHRP2RX7ERCC5FEN1PKM
SCHEMBL31502517 0.83 TSHR (0.62) TSHRP2RX7ERCC5FEN1PKM
SCHEMBL2831621 0.83 TSHR (0.68) TSHRP2RX7ERCC5FEN1PKM
SCHEMBL97298 0.83 TSHR (1.00) TSHRP2RX7ERCC5FEN1ALDH1A1
SCHEMBL29904615 0.83 TSHR (1.00) TSHRP2RX7ERCC5FEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109763314-B UV-thermal dual-curing colored coating method for UHMPE fiber tows 山东鲁普科技有限公司 2021-11-19 CN claimed
CN-110511163-B Method for preparing polyisocyanate by photochemical reaction and method for preparing aqueous polyurethane resin 万华化学集团股份有限公司 2021-09-07 CN claimed
WO-2021042251-A1 METHOD FOR PREPARATION OF POLYISOCYANATE BY PHOTOCHEMICAL REACTION AND METHOD FOR PREPARING WATERBORNE POLYURETHANE RESIN 万华化学集团股份有限公司 2021-03-11 WO claimed
CN-110003200-A P2X7 regulator 詹森药业有限公司 2019-07-12 CN claimed
CN-105209464-B P2X7 modulators 詹森药业有限公司 2019-01-01 CN claimed
CN-105209464-A P2x7 modulators JANSSEN PHARMACEUTICA NV 2015-12-30 CN claimed
CN-103748076-A ROR gamma T inhibitors MERCK SHARP & DOHME 2014-04-23 CN claimed
WO-2001094452-A2 UV CURABLE COATING FOR GOLF BALLS LORD CORPORATION (US) 2001-12-13 WO claimed
US-20250052765-A1 Nanobody Discovery Platform and Related Methods CARNEGIE MELLON UNIVERSITY 2025-02-13 US disclosed
WO-2023111983-A1 NANOBODY DISCOVERY PLATFORM AND RELATED METHODS CARNEGIE MELLON UNIVERSITY (US) 2023-06-22 WO disclosed
CN-109763314-B UV-thermal dual-curing colored coating method for UHMPE fiber tows 山东鲁普科技有限公司 2021-11-19 CN disclosed
CN-110511163-B Method for preparing polyisocyanate by photochemical reaction and method for preparing aqueous polyurethane resin 万华化学集团股份有限公司 2021-09-07 CN disclosed
CN-112646461-A LED-UV (light-emitting diode-ultraviolet) photocureable nano-coating for piano surface and preparation method thereof 山东大学 2021-04-13 CN disclosed
WO-2021042251-A1 METHOD FOR PREPARATION OF POLYISOCYANATE BY PHOTOCHEMICAL REACTION AND METHOD FOR PREPARING WATERBORNE POLYURETHANE RESIN 万华化学集团股份有限公司 2021-03-11 WO disclosed
EP-0066543-B1 THERMALLY POLYMERIZABLE COMPOSITIONS AND PROCESS FOR THE THERMAL POLYMERIZATION OF CATIONICALLY POLYMERIZABLE COMPOUNDS CIBA-GEIGY AG (CH) 1985-11-27 EP disclosed
EP-0147299-A2 Process for the preparation of benzophenones RHONE-POULENC CHIMIE (FR) 1985-07-03 EP disclosed
US-4393185-A EPOXIDES CIBA-GEIGY CORPORATION (US) 1983-07-12 US disclosed
EP-0066543-A2 Thermally polymerizable compositions and process for the thermal polymerization of cationically polymerizable compounds CIBA-GEIGY AG (CH) 1982-12-08 EP disclosed
US-4207266-A CARBON TETRALIDE, HYDROGEN FLUORIDE, LEWIS ACID AD AROMATIC HYDROCARBON ROHM AND HAAS COMPANY (US) 1980-06-10 US disclosed
US-3956324-A THERMOPLASTIC POLYMER CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250052765-A1 Nanobody Discovery Platform and Related Methods CD2BP2, VAPB, VPS4B TSHR 2312/4885P2RX7 4378/4885ERCC5 1750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.