Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028027 | 0.88 | ANPEP (0.43) | ANPEPRNPEPDNPEPMMP1LTA4H | |
| SCHEMBL7028776 | 0.86 | ANPEP (0.34) | ANPEPRNPEPDNPEPPSMB5LTB4R2 | |
| SCHEMBL7029135 | 0.86 | MMP2 (0.36) | ANPEPLTB4R2LTA4H | |
| SCHEMBL7032152 | 0.85 | MARS1 (0.35) | — | |
| SCHEMBL7029892 | 0.77 | MMP2 (0.37) | ANPEPRNPEPDNPEPLTA4HREN | |
| SCHEMBL4398840 | 0.76 | ANPEP (0.38) | ANPEPRNPEPDNPEPLTA4HLARS1 | |
| SCHEMBL7031217 | 0.75 | MARS1 (0.36) | — | |
| SCHEMBL7999637 | 0.75 | ANPEP (0.51) | ANPEPRNPEPDNPEPLTA4HACE | |
| SCHEMBL7030791 | 0.74 | ANPEP (0.40) | ANPEPRNPEPDNPEPLTB4R2LTA4H | |
| SCHEMBL19974077 | 0.73 | ANPEP (0.51) | ANPEPRNPEPDNPEPLTA4HACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140984-B1 | SELECTIVE INHIBITORS OF MMP-12 | AVENTIS PHARMA INC (US) | 2003-02-12 | — | — | EP | disclosed |
| US-6352976-B1 | ENZYME INHIBITORS OF MATRIX METALLOPROTEINASE FOR EMPHYSEMA | AVENTIS PHARMACEUTICALS INC. | 2002-03-05 | — | — | US | disclosed |
| EP-1140984-A1 | SELECTIVE INHIBITORS OF MMP-12 | Aventis Pharmaceuticals Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040600-A1 | SELECTIVE INHIBITORS OF MMP-12 | AVENTIS PHARMACEUTICALS INC. (US) | 2000-07-13 | — | — | WO | disclosed |