Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 8/20 | 0.34 |
| ▸ | FNTB | P49356 | 8/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029135 | 0.87 | MMP2 (0.36) | — | |
| SCHEMBL7031217 | 0.87 | MARS1 (0.36) | MARS1FNTAFNTBPGGT1B | |
| SCHEMBL7026570 | 0.87 | LTB4R2 (0.32) | MARS1FNTAFNTBPGGT1B | |
| SCHEMBL7032099 | 0.85 | ANPEP (0.37) | — | |
| SCHEMBL7029892 | 0.75 | MMP2 (0.37) | — | |
| SCHEMBL7032492 | 0.74 | MMP2 (0.34) | — | |
| SCHEMBL7027416 | 0.74 | FNTA (0.33) | MARS1FNTAFNTBPGGT1B | |
| SCHEMBL7028027 | 0.73 | ANPEP (0.43) | — | |
| SCHEMBL7028776 | 0.72 | ANPEP (0.34) | — | |
| SCHEMBL39530 | 0.71 | ANPEP (0.37) | MARS1FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140984-B1 | SELECTIVE INHIBITORS OF MMP-12 | AVENTIS PHARMA INC (US) | 2003-02-12 | — | — | EP | disclosed |
| US-6352976-B1 | ENZYME INHIBITORS OF MATRIX METALLOPROTEINASE FOR EMPHYSEMA | AVENTIS PHARMACEUTICALS INC. | 2002-03-05 | — | — | US | disclosed |
| EP-1140984-A1 | SELECTIVE INHIBITORS OF MMP-12 | Aventis Pharmaceuticals Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040600-A1 | SELECTIVE INHIBITORS OF MMP-12 | AVENTIS PHARMACEUTICALS INC. (US) | 2000-07-13 | — | — | WO | disclosed |