Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL11105589 | 0.65 | LMNA (0.52) | PTPN1GSK3AGSK3BGAANPC1 | |
| SCHEMBL9350357 | 0.65 | MGLL (0.39) | PTPN1GSK3AGSK3BGAAMGLL | |
| SCHEMBL17195399 | 0.64 | PTPN1 (0.50) | PTPN1GSK3AGSK3BGAANPC1 | |
| SCHEMBL31006735 | 0.63 | PTPN1 (0.44) | PTPN1GSK3AGSK3BGAAMGLL | |
| SCHEMBL8128786 | 0.59 | GSK3A (0.54) | GSK3AGSK3BGAAMGLLSMN1; SMN2 | |
| SCHEMBL447261 | 0.58 | GSK3A (1.00) | GSK3AGSK3BGAAMGLLSMN1; SMN2 | |
| SCHEMBL3655311 | 0.58 | TSHR (0.48) | GSK3AGSK3BGAAMGLLSMN1; SMN2 | |
| Potassium SCHEMBL11261679 | 0.58 | GSK3A (0.52) | GSK3AGSK3BGAAMGLLSMN1; SMN2 | |
| SCHEMBL27740275 | 0.58 | GAA (0.46) | GSK3AGSK3BGAAMGLLSMN1; SMN2 | |
| SCHEMBL1722780 | 0.57 | GSK3B (0.71) | GSK3AGSK3BGAAMGLLNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412364-A1 | PLATELET ADP RECEPTOR INHIBITORS | Portola Pharmaceuticals, Inc. (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011872-A1 | PLATELET ADP RECEPTOR INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-02-13 | — | — | WO | disclosed |