SCHEMBL7032791

SCHEMBL7032791

CC(C)(c1ccc(O)cc1)c1ccc(OC(Oc2ccc(C(C)(C)c3ccc(O)cc3)cc2)(Oc2ccc(C(C)(C)c3ccc(O)cc3)cc2)Oc2ccc(C(C)(C)c3ccc(O)cc3)cc2)cc1.Oc1ccc(C(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccc(O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 9/20 0.59
ESR1 P03372 9/20 0.59
CYP3A4 P08684 3/20 0.59
AR P10275 1/20 0.59
HPGD P15428 1/20 0.59
TSHR P16473 1/20 0.59
SLC6A2 P23975 1/20 0.59
SLC6A4 P31645 1/20 0.59
HTR6 P50406 1/20 0.59
ESRRG P62508 1/20 0.59
SLC6A3 Q01959 1/20 0.59
HSD17B10 Q99714 1/20 0.59
ALDH1A1 P00352 2/20 0.52
LMNA P02545 1/20 0.48
TYR P14679 1/20 0.48
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
SHBG P04278 1/20 0.37
LTA4H P09960 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24487 0.94 ESR2 (0.67) ESR2ESR1CYP3A4ARHPGD
SCHEMBL13416164 0.84 ESR1 (0.84) ESR2ESR1CYP3A4ARHPGD
SCHEMBL12204980 0.82 ESR2 (0.67) ESR2ESR1CYP3A4ARHPGD
SCHEMBL2483852 0.81 ESR2 (0.64) ESR2ESR1CYP3A4ARHPGD
SCHEMBL7929165 0.79 ESR1 (0.61) ESR2ESR1CYP3A4ARHPGD
SCHEMBL7937266 0.79 ESR2 (0.61) ESR2ESR1CYP3A4ARHPGD
SCHEMBL10865719 0.78 ESR1 (0.73) ESR2ESR1CYP3A4ARHPGD
SCHEMBL4450783 0.78 ESR1 (0.73) ESR2ESR1CYP3A4ARHPGD
Bisphenol A SCHEMBL9774987 0.77 ESR1 (1.00) ESR2ESR1CYP3A4ARHPGD
Bisphenol A SCHEMBL3170263 0.77 ESR1 (1.00) ESR2ESR1CYP3A4ARHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0472168-B1 Allyl ester oligomer composition and organic glass for optical material comprising same SHOWA DENKO KK (JP) 1995-08-02 EP claimed
EP-0712888-B1 Color-stable polycarbonate composition and articles molded therefrom BAYER AG (US) 2003-02-19 EP disclosed
US-20030013788-A1 Melt polycarbonate with improved resistance to hydrolysis BAYER AKTIENGESELLSCHAF (DE) 2003-01-16 US disclosed
US-RE37200-E1 THERMOPLASTIC MOLDING COMPOSITION BAYER CORPORATION 2001-05-29 US disclosed
EP-0712888-A1 Color-stable polycarbonate composition and articles molded therefrom Bayer Corporation (US) 1996-05-22 EP disclosed
US-5484828-A MULTILAYER LAMINATE WITH RESISTANCE TO DISCOLORATION WITH PROTECTIVE FILMS BAYER CORPORATION (US) 1996-01-16 US disclosed
EP-0683208-A2 Transparent polycarbonate polyester blends Bayer Corporation (US) 1995-11-22 EP disclosed
US-5461120-A Blend of a copolyester with a polycarbonate BAYER CORPORATION (US) 1995-10-24 US disclosed
EP-0653462-A2 Transparent polycarbonate PBT blends Bayer Corporation (US) 1995-05-17 EP disclosed
US-5401813-A INCREASING THE TOTAL LIGHT TRANSMISSION OF A THERMOPLASTIC MOLDING MATERIAL BY BLENDING POLYBUTYLENE TEREPHTHALATE AND TWO AROMATIC POLYCARBONATES IN SPECIFIED AMOUNTS MILES INC. (US) 1995-03-28 US disclosed
US-5376736-A Second polycarbonate contains cyclic bridging unit MILES INC. (US) 1994-12-27 US disclosed
EP-0338355-B1 SOILING-RESISTANT POLYCARBONATE PLATES MILES INC. (US) 1992-11-11 EP disclosed
US-5100889-A Thromboxane A2 receptor antagonists, thromboxane synthetase inhibitor E. R. SQUIBB & SONS, INC. (US) 1992-03-31 US disclosed
US-4948666-A Stain resistant polycarbonate panels MOBAY CORPORATION (US) 1990-08-14 US disclosed
EP-0338355-A1 Soiling-resistant polycarbonate plates MILES INC. (US) 1989-10-25 EP disclosed