SCHEMBL7032877

SCHEMBL7032877

C[Si](C)(Cl)CCCC/C=C/CCCC[Si](C)(C)Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.32
TRPV1 Q8NER1 1/20 0.32
TOP1 P11387 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7032881 1.00 FAAH (0.32) FAAHTRPV1TOP1
SCHEMBL7042281 0.91 FAAH (0.41) FAAHTRPV1TOP1
SCHEMBL7043059 0.91 FAAH (0.41) FAAHTRPV1TOP1
SCHEMBL706918 0.82 ALDH1A1 (0.39)
SCHEMBL297100 0.79 TSHR (0.44)
SCHEMBL7033754 0.79 TSHR (0.44) FAAHTRPV1
SCHEMBL8158855 0.78 ALDH1A1 (0.36)
SCHEMBL8166184 0.78 ALDH1A1 (0.36)
SCHEMBL8165493 0.78 ALDH1A1 (0.36)
SCHEMBL8169552 0.78 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0857727-B1 Polymerization of vinyl monomers from silanes and siloxanes DOW CORNING (US) 2003-04-02 EP claimed
EP-0857727-A2 Polymerization of vinyl monomers from silanes and siloxanes DOW CORNING CORPORATION (US) 1998-08-12 EP claimed
US-5708115-A OZONIDE GROUPS, FREE RADICAL CATALYSTS DOW CORNING CORPORATION (US) 1998-01-13 US claimed
EP-0857727-B1 Polymerization of vinyl monomers from silanes and siloxanes DOW CORNING (US) 2003-04-02 EP disclosed
EP-0863146-B1 Method of making organosilicon carbonyl compounds DOW CORNING (US) 2003-02-19 EP disclosed
US-5880304-A Method of making organosilicon carbonyl compounds DOW CORNING CORPORATION (US) 1999-03-09 US disclosed
EP-0870774-A2 Method of making silicone-organic block copolymers DOW CORNING CORPORATION (US) 1998-10-14 EP disclosed
EP-0863146-A2 Method of making organosilicon carbonyl compounds DOW CORNING CORPORATION (US) 1998-09-09 EP disclosed
EP-0857727-A2 Polymerization of vinyl monomers from silanes and siloxanes DOW CORNING CORPORATION (US) 1998-08-12 EP disclosed
US-5789516-A ADDITION-CONDENSATION POLYMERS DOW CORNING CORPORATION (US) 1998-08-04 US disclosed
US-5789503-A Polymerization of vinyl monomers from silanes and siloxanes DOW CORNING CORPORATION (US) 1998-08-04 US disclosed
US-5708115-A OZONIDE GROUPS, FREE RADICAL CATALYSTS DOW CORNING CORPORATION (US) 1998-01-13 US disclosed