Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13789644 | 0.92 | — | — | |
| SCHEMBL5665688 | 0.81 | — | — | |
| SCHEMBL7032877 | 0.79 | FAAH (0.32) | FAAHTRPV1 | |
| SCHEMBL7032881 | 0.79 | FAAH (0.32) | FAAHTRPV1 | |
| SCHEMBL706918 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL12354498 | 0.77 | TSHR (0.52) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL10787403 | 0.77 | TSHR (0.52) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL27055257 | 0.77 | TSHR (0.52) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL297100 | 0.75 | TSHR (0.44) | TSHRALDH1A1HPGD | |
| SCHEMBL175548 | 0.74 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870774-A2 | Method of making silicone-organic block copolymers | DOW CORNING CORPORATION (US) | 1998-10-14 | — | — | EP | claimed |
| US-5789516-A | ADDITION-CONDENSATION POLYMERS | DOW CORNING CORPORATION (US) | 1998-08-04 | — | — | US | claimed |
| EP-0863146-B1 | Method of making organosilicon carbonyl compounds | DOW CORNING (US) | 2003-02-19 | — | — | EP | disclosed |
| US-5880304-A | Method of making organosilicon carbonyl compounds | DOW CORNING CORPORATION (US) | 1999-03-09 | — | — | US | disclosed |
| EP-0870774-A2 | Method of making silicone-organic block copolymers | DOW CORNING CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| EP-0863146-A2 | Method of making organosilicon carbonyl compounds | DOW CORNING CORPORATION (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5789516-A | ADDITION-CONDENSATION POLYMERS | DOW CORNING CORPORATION (US) | 1998-08-04 | — | — | US | disclosed |