Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13647585 | 0.88 | FDPS (0.47) | ALDH1A1LMNAMAPK1TDP1CYP3A4 | |
| SCHEMBL7031543 | 0.86 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPK1TDP1CYP3A4 | |
| SCHEMBL7028569 | 0.85 | FDPS (0.57) | ALDH1A1LMNATDP1TSHRHPGD | |
| SCHEMBL7024760 | 0.85 | ALDH1A1 (0.53) | ALDH1A1AOX1LMNAMAPK1TDP1 | |
| SCHEMBL17264216 | 0.83 | ALDH1A1 (0.41) | ALDH1A1AOX1LMNAMAPK1TDP1 | |
| SCHEMBL9130383 | 0.82 | ALDH1A1 (0.41) | ALDH1A1AOX1LMNAMAPK1TDP1 | |
| SCHEMBL9130390 | 0.82 | ALDH1A1 (0.41) | ALDH1A1AOX1LMNAMAPK1TDP1 | |
| SCHEMBL1425314 | 0.81 | ALDH1A1 (0.60) | ALDH1A1AOX1LMNATDP1TSHR | |
| SCHEMBL5216212 | 0.79 | ALDH1A1 (0.58) | ALDH1A1AOX1TDP1TTRTRIM24 | |
| SCHEMBL3842399 | 0.78 | ALDH1A1 (0.57) | ALDH1A1AOX1TDP1TTRTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576974-B1 | Benzyliden-quinuclidinones as sunscreen agents | MERCK PATENT GMBH (DE) | 2003-02-05 | — | — | EP | disclosed |