Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1453733 | 0.83 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL7705601 | 0.76 | TSHR (0.34) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL7597879 | 0.75 | ALDH1A1 (0.33) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL7943578 | 0.75 | TSHR (0.38) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL7807946 | 0.73 | ALDH1A1 (0.32) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL1454464 | 0.72 | PTAFR (0.33) | — | |
| SCHEMBL1452916 | 0.72 | TERT (0.35) | KIF11 | |
| SCHEMBL7597881 | 0.72 | ALDH1A1 (0.32) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL1452745 | 0.71 | NPC1 (0.30) | ALDH1A1 | |
| SCHEMBL31536926 | 0.71 | KIF11 (0.40) | ALDH1A1KIF11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |
| US-5869584-A | Process for the preparation of an olefin polymer using metallocenes containing specifically substituted indenyl ligands | TARGOR GMBH (DE) | 1999-02-09 | — | — | US | disclosed |
| EP-0582194-B1 | Process for the preparation of polymers using metallocenes with specifically substituted indenyl ligands | TARGOR GMBH (DE) | 1998-05-06 | — | — | EP | disclosed |
| EP-0582194-A1 | Process for the preparation of polymers using metallocenes with specifically substituted indenyl ligands | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-09 | — | — | EP | disclosed |