Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.30 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.30 |
| ▸ | COMT | P21964 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025330 | 0.86 | DAO (0.41) | CA12CA1CA2CA9CA7 | |
| SCHEMBL7033439 | 0.86 | CES2 (0.39) | MELKCA12CA1CA2CA9 | |
| SCHEMBL7026719 | 0.85 | CTPS1 (0.44) | MELKCTPS1POLBMAPTNPSR1 | |
| SCHEMBL7024257 | 0.85 | CA12 (0.32) | CA12CA1CA2CA9CA7 | |
| SCHEMBL7029049 | 0.84 | MEN1 (0.34) | CA12CA1CA2CA9CA7 | |
| SCHEMBL7031595 | 0.84 | HPGD (0.35) | CA12CA1CA2CA9CA7 | |
| SCHEMBL7032161 | 0.82 | CA12 (0.31) | CA12CA1CA2CA9CA7 | |
| SCHEMBL7031154 | 0.82 | POLB (0.39) | CA12CA1CA2CA9POLB | |
| SCHEMBL7028004 | 0.81 | TRPA1 (0.30) | CA12CA1CA2CA9CA7 | |
| SCHEMBL7030226 | 0.81 | ABL1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162979-A1 | Substituted sulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-08-28 | — | — | US | disclosed |
| US-6441195-B1 | 2-ALKOXYCARBONYL-3-SULPHONAMIDE, SULPHONYL ISOCYANATE OR SULPHONYL ISOTHIOCYANATE-THIOPHENES; PRE- OR POSTEMERGENCE HERBICIDES; EFFICIENCY | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | disclosed |
| US-6180567-B1 | REACTING 2-ALKOXYCARBONYL-BENZENESULFONAMIDE DERIVATIVE WITH 1,2,4-(1H)TRIAZOLE-5-(THI)ONE DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162979-A1 | Substituted sulphonylamino(thio)carbonyl compounds | CBR3, CTH, CBR1 | MELK 3618/4885CTPS1 184/4885CA12 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.