Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SELL | P14151 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | SELE | P16581 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1494319 | 0.85 | SELL (0.52) | LMNASELLSELPSELEACHE | |
| SCHEMBL27864186 | 0.83 | SELL (0.50) | LMNASELLSELPSELEACHE | |
| SCHEMBL12295394 | 0.83 | LMNA (0.38) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL13748754 | 0.79 | TSHR (0.52) | LMNACHRM1SLC6A2ADRA1AHTR2B | |
| SCHEMBL3060235 | 0.79 | SELL (0.46) | LMNASELLSELPSELEACHE | |
| SCHEMBL24838149 | 0.77 | GABRA1 (0.48) | LMNATRPA1ALDH1A1KDM4EGAA | |
| SCHEMBL1487428 | 0.77 | LMNA (0.54) | LMNASELLSELPSELEACHE | |
| SCHEMBL12237882 | 0.76 | LMNA (0.39) | LMNAALDH1A1KMT2APOLBMAPT | |
| SCHEMBL27595492 | 0.76 | ALDH1A1 (0.45) | LMNASELLSELPSELEACHE | |
| SCHEMBL24248982 | 0.76 | SELL (0.48) | LMNASELLSELPSELEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | claimed |
| CN-108026077-A | PHENOXYMETHYL DERIVATIVES | 豪夫迈·罗氏有限公司 | 2018-05-11 | — | — | CN | disclosed |
| EP-2787819-A2 | MICROBICIDAL COMPOSITION | Unilever N.V. (NL) | 2014-10-15 | — | — | EP | disclosed |
| WO-2013083586-A2 | MICROBICIDAL COMPOSITION | UNILEVER N.V. (NL) | 2013-06-13 | — | — | WO | disclosed |