Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.91 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.91 |
| ▸ | LMNA | P02545 | 2/20 | 0.91 |
| ▸ | PKM | P14618 | 4/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642133 | 0.95 | MAPT (1.00) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL9721028 | 0.93 | KDM4E (0.81) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL9720952 | 0.93 | KDM4E (0.81) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL783687 | 0.93 | KDM4E (0.81) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL1250581 | 0.92 | KDM4E (0.82) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL7608611 | 0.90 | KDM4E (0.85) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL7033532 | 0.88 | MAPT (0.72) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL8601357 | 0.87 | KDM4E (1.00) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL18459774 | 0.85 | MAPT (0.76) | MAPTALDH1A1KCNJ1LMNAPKM | |
| SCHEMBL521103 | 0.84 | PKM (0.75) | MAPTALDH1A1KCNJ1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6048942-A | — | — | None | — | — | JP | disclosed |
| EP-0583665-B1 | Pharmaceutical composition and method for treating hyperlipidemia and arteriosclerosis | FUJI PHOTO FILM CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-5387600-A | Anticholesterol agents; antilipemic agents | FUJI PHOTO FILM CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583665-A2 | Pharmaceutical composition and method for treating hyperlipidemia and arteriosclerosis | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-23 | — | — | EP | disclosed |
| JP-H0648942-A | ANTIHYPERLIPEMIA PREPARATION AND ANTIARTERIOSCLORETIC PREPARATION | FUJI PHOTO FILM CO LTD | 1994-02-22 | — | — | JP | disclosed |