Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.58 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 8/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967029 | 0.88 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDCA12CA1 | |
| SCHEMBL1998827 | 0.84 | MAOB (0.50) | KDM4EALDH1A1HPGDCA12CA1 | |
| SCHEMBL5298419 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1HPGDCA12CA1 | |
| SCHEMBL5298416 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1HPGDCA12CA1 | |
| SCHEMBL28540129 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1HPGDCA12CA1 | |
| SCHEMBL5858393 | 0.79 | MAOB (0.57) | KDM4EALDH1A1HPGDCA12CA1 | |
| SCHEMBL12839872 | 0.79 | MAOB (0.64) | KDM4EALDH1A1HPGDCA12CA1 | |
| SCHEMBL29985195 | 0.79 | APP (0.60) | KDM4EALDH1A1HPGDCA12CA1 | |
| SCHEMBL120294 | 0.79 | APP (0.60) | KDM4EALDH1A1HPGDCA12CA1 | |
| SCHEMBL5294404 | 0.78 | ADAM17 (0.56) | KDM4EALDH1A1HPGDCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322308-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | Durect Corporation (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002028366-A9 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORP (US) | 2003-02-13 | — | — | WO | disclosed |
| WO-2002028366-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |