Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.61 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.61 |
| ▸ | ABAT | P80404 | 1/20 | 0.61 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.61 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909451 | 0.86 | CYP2C9 (0.62) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL359439 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL18310141 | 0.84 | TRPA1 (0.59) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL15652453 | 0.84 | ALDH1A1 (0.65) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL29268876 | 0.81 | ALDH1A1 (0.85) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL25214183 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL3320296 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL31251381 | 0.79 | ALDH1A1 (0.62) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL19699322 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDTDP1TRIM24 | |
| SCHEMBL9958266 | 0.79 | KDM4E (0.45) | ALDH1A1TSHRHPGDTDP1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030230478-A1 | Process for the preparation of 1,4 - dihydropyridines and novel 1,4-dihydropyridines useful as therapeutic agents | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030230478-A1 | Process for the preparation of 1,4 - dihydropyridines and novel 1,4-dihydropyridines useful as therapeutic agents | HRH4, ODC1, OGDH | ALDH1A1 29/4885TSHR 2934/4885HPGD 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.