Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 5/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039890 | 0.82 | PDE5A (0.42) | ADORA1PDE5APDE3APDE4B | |
| SCHEMBL7035541 | 0.81 | ADORA1 (0.45) | ADORA1PDE5APDE3APDE4B | |
| SCHEMBL7036909 | 0.77 | ADORA1 (0.43) | ADORA1PDE5APDE3APDE4B | |
| SCHEMBL7033867 | 0.74 | ADORA1 (0.47) | ADORA1PDE5APDE3A | |
| SCHEMBL7032843 | 0.74 | PDE5A (0.40) | ADORA1PDE5APDE3APDE4B | |
| SCHEMBL7038474 | 0.73 | PDE5A (0.41) | ADORA1PDE5APDE3APDE4B | |
| SCHEMBL7038368 | 0.72 | ADORA1 (0.48) | ADORA1PDE5APDE3APDE4B | |
| SCHEMBL7036654 | 0.72 | ADORA1 (0.44) | ADORA1PDE5APDE3APDE4B | |
| SCHEMBL7037944 | 0.72 | PDE5A (0.42) | ADORA1PDE5APDE3APDE4B | |
| SCHEMBL7035962 | 0.71 | ADORA1 (0.43) | ADORA1PDE5APDE3APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004494-A1 | PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-16 | — | — | WO | disclosed |